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Ingestion of the Hoodia plant has no known reported side effects , although its taste is considered to be unpleasant and bitter. But the pharmaceutical firm Phizer, which had teamed with Phytopharm and funded much of the research on Hoodia, dropped out of the project because of beliefs that it wouldn't be realistic to make pills out of the active ingredient in the Hoodia plant. Hoodia is grows in extremely hot conditions, and the plant takes years to reach maturity. In order to increase its very limited supply, Phytopharm has established Hoodia plantations in South Africa, which are trying to establish cultivation and farming methods to grow the wild plant. And found no discernible evidence that the pills contained any active Hoodia. Phytopharm states that assays of "Hoodia" supplements from different companies show that these contain between 0.1 and 0.01 percent of the active ingredient claimed, according to a CBS report in 2004. The FDA has warned manufacturers of products claiming to contain Hoodia that its effectiveness and safety have not been determined in humans. Double-blinded clinical trials are required to establish the safety and effectiveness of any product, and these have not yet been completed with Hoodia. more...



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Research on African mango shows beneficial effects for diabetes and obesity, as well as analgesic, antimicrobial, antioxidant, and GI activity. Numerous studies exist on the potential industrial application of African mango in food, cosmetic, and pharmaceutical products. African Mango Uses and Pharmacology. Research on African mango revealed beneficial effects on diabetes and obesity as well as antimicrobial, antioxidant, and GI activity. Oral administration of an African mango methanol extract at a dose of 150 and 250 mg/kg significantly ( P < 0.001) lowered plasma glucose levels in diabetic rats within 2 hours after treatment. 34 Postprandial and fasting glucose levels were reduced in normoglycemic rats administered African mango seed fractions prior to an oral glucose test. Rats were fed a normal diet and 1 m L of African mango oil or water over 4 weeks. Controlled study of 102 overweight patients evaluated the effects of African mango seed extract on body weight and associated metabolic parameters. 39 Patients received either 150 mg of African mango seed extract or placebo 30 minutes before lunch and dinner. Controlled, crossover study examined the effects of African mango seed extract in 40 obese patients. more...



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