Max Dose Of Topamax For Weight Loss


Topamax dosage for weight loss

Topamax dosage for weight loss. Common Questions and Answers about Topamax dosage for weight loss. I have been taking Topamax for weight loss for almost two months and have lost 20 pounds and feel great. After that the weight loss slowed and then stopped. I am more concerned that it works for the headache than weight loss at this point for me. I would not recommend Topamax or any other drug for weight loss , particularly if the need is minimal. I read that one of the side effects of topamax is weight loss . I have tried topamax several times for weight loss . She told me that Topamax is responsible for about a 10 lb weight loss and that is it. I have also been prescribed topamax for pain, mood stabilizer and weight loss so I have been looking a lot on the net. My understanding from the drug handout is that it is normally prescribed for migraines, seizures and weight loss . What is the relationship between dosage and weight loss ? Does any one taking topamax for migraines have the problem of memory loss ? more...



Topamax - Side Effects, Dosage, Interactions - Everyday Health

Topamax is the brand name of topiramate, an anticonvulsant drug used to prevent seizures and reduce the frequency of migraines . The Food and Drug Administration (FDA) approved Topamax to treat seizures in 1996. Topamax and Weight Loss. Pregnancy and Topamax (Topiramate) Topamax (Topiramate) Side Effects. Some side effects of Topamax may disappear after your body gets used to the medication. Topamax (Topiramate) and Alcohol. This is not a complete list of the side effects associated with Topamax. Q: What is Topamax, and what are the side effects of this drug? These are not all the possible side effects of Topamax. Also fatigue and sedation are common with Topamax. more...



Talking With Your Doctor - TOPAMAX

TOPAMAX® may cause decreased sweating and increased body temperature (fever). TOPAMAX® can increase the level of acid in your blood (metabolic acidosis). If left untreated, metabolic acidosis can cause brittle or soft bones (osteoporosis, osteomalacia, osteopenia), kidney stones, can slow the rate of growth in children, and may possibly harm your baby if you are pregnant. Your healthcare provider should do a blood test to measure the level of acid in your blood before and during your treatment with TOPAMAX®. If you are pregnant, you should talk to your healthcare provider about whether you have metabolic acidosis. TOPAMAX® can harm your unborn baby. If you take TOPAMAX® during pregnancy, your baby has a higher risk for birth defects called cleft lip and cleft palate. Tell your healthcare provider right away if you become pregnant while taking TOPAMAX®. You and your healthcare provider should decide if you will continue to take TOPAMAX® while you are pregnant. Talk to your healthcare provider if TOPAMAX® has caused metabolic acidosis during your pregnancy. If you become pregnant while taking TOPAMAX®, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry. TOPAMAX® can slow your thinking and motor skills and may affect vision. These are not all the possible side effects of TOPAMAX®. more...



Topamax Drug Information : Indications, Dosage

TOPAMAX® (topiramate) Tablets are available as debossed, coated, round tablets in the following strengths and colors: 15 mg capsule with “TOP” and “15 mg” on the side. 25 mg capsule with “TOP” and “25 mg” on the side. TOPAMAX® Tablets TOPAMAX® (topiramate) Tablets are available as debossed, coated, round tablets in the following strengths and colors: 25 mg cream tablet (debossed “OMN” on one side; “25” on the other) and are available in bottles of 60 count with desiccant (NDC 50458-639-65) 50 mg light yellow tablet (debossed “OMN” on one side; “50” on the other) and are available in bottles of 60 count with desiccant (NDC 50458-640-65) 100 mg yellow tablet (debossed “OMN” on one side; “100” on the other) and are available in bottles of 60 count with desiccant (NDC 50458-641-65) 200 mg salmon tablet (debossed “OMN” on one side; “200” on the other) and are available in bottles of 60 count with desiccant (NDC 50458-642-65) 15 mg capsule with “TOP” and “15 mg” on the side and are available in bottles of 60 (NDC 50458-647-65) 25 mg capsule with “TOP” and “25 mg” on the side and are available in bottles of 60 (NDC 50458-645-65) more...



How Does Topamax Help Weight Loss

How Does Topamax Help Weight Loss? Topamax is an anti-seizure drug that can cause weight loss. Many Topamax users have experienced quick success when taking Topamax for weight loss. While the specific mechanism of how Topamax brings about weight loss is not yet understood, doctors and researchers have several theories. During clinical trials of Topamax, one of the most common side effects was significant weight loss. Topiramate has never received FDA approval for the treatment of weight loss, and all weight-loss treatment is off-label. Weight loss was one of the most common side effects of Topamax, occurring in between 11 and 26 percent of patients taking the drug. According to Ortho-Mc Neil's Topamax website, some patients lose weight while taking Topamax, and the amount of weight loss varies according to the dosage taken. Brian Loftus states that some patients lose as much as 15 to 20 percent of their body weight while taking between 100 and 200 mg Topamax, and they report that the weight loss is effortless. The specific mechanism of weight loss resulting from topiramate is unknown; however, there are some common theories about how Topamax helps to facilitate weight loss. In some patients, this change in taste may be so severe that they lose the pleasure associated with food, which may lead to weight loss. Another theory supported by the American Diabetes Association discusses how Topamax may act on blood glucose and insulin secretion, which can lead to weight loss through ketosis. more...



Phentermine and Topiramate : MedlinePlus Drug Information

Your doctor will probably start you on a low dose of phentermine and topiramate and increase your dose after 14 days. If you have not lost a certain amount of weight, your doctor may tell you to stop taking phentermine and topiramate or may increase your dose and then increase it again after 14 days. If you have not lost a certain amount of weight, it is not likely that you will benefit from taking phentermine and topiramate, so your doctor will probably tell you to stop taking the medication. Phentermine and topiramate will help control your weight only as long as you continue to take the medication. Do not stop taking phentermine and topiramate without talking to your doctor. Your doctor will probably tell you not to take phentermine and topiramate if you are taking one or more of these medications or have taken one of these medications during the past 2 weeks. Your doctor will probably tell you not to take phentermine and topiramate. If you become pregnant while taking phentermine and topiramate, stop taking the medication and call your doctor immediately. If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking phentermine and topiramate. You should know that phentermine and topiramate may slow your thinking and movements and affect your vision. more...



Topamax oral : Uses, Side Effects, Interactions, Pictures

If you have any questions, ask your doctor or pharmacist. It may take several weeks or months to reach the best dose for you and to get the full benefit from this medication. Do not stop taking this medication without consulting your doctor. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects. Before taking topiramate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This drug may make you dizzy or drowsy or impair your judgment. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately talk to your doctor about the benefits and risks of using this medication during pregnancy. If you are taking this drug to treat seizures, note that untreated seizures are a serious condition that can harm both a pregnant woman and her unborn baby, so do not stop taking this medication unless directed by your doctor. Drug interactions may change how your medications work or increase your risk for serious side effects. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. more...



Topiramate , Mood Disorders and PTSD

Warning: The primary use of Topiramate, and the only use for which it has regulatory approval, is to treat seizures. However, no peer-reviewed studies have established that Topiramate is safe and effective for those conditions, and therefore these uses have not been approved by the FDA. Secondly, the set of side effects that patients may experience is quite different on Topiramate compared to other mood stabilizers. How is Topiramate different from carbamazepine and valproate? Some psychiatrists have reported using Topiramate to help relieve the symptoms of PTSD and the side effects related to eating that other psychiatric drugs can create. However, carbamazepine can lower the blood-plasma level of Topiramate by 50 percent and valproate can lower it by 15 percent. Topiramate itself can lower the blood-plasma level of valproate by 10 percent. Thus far, there are no known interactions for patients taking Topiramate and either lamotrigine or gabapentin. What final doses of Topiramate are typical and what doses are appropriate for different disorders? The final doses of Topiramate vary widely based on the targeted disorder, the patient, and whether or not the patient is taking any other drugs at the same time. How long until the patient feels the effects of Topiramate? What is the side effect profile of Topiramate? more...



Topiramate, Topamax for Migraine Side Effects and Dosage

DRUG CLASS AND MECHANISM: Topiramate is an oral drug that is used to prevent the seizures of epilepsy . Seizures are due to the abnormal activity ("firing") of nerves in the brain, and the abnormal activity spreads to smaller or larger portions of the brain. By altering the production or action of the neurotransmitters, topiramate may suppress the abnormal activity of the nerves in the brain that cause the seizures or may prevent the abnormal activity from spreading to other nerves. Other studies suggest that topiramate may suppress the nerves directly (i.e., not by altering neurotransmitters) and make them less likely to fire. The FDA approved topiramate as a tablet in 1997. Topiramate also is used in patients 2 years of age and older with seizures associated with the Lennox-Gastaut syndrome, a severe form of epilepsy which accounts for up to 10% of all cases of childhood epilepsy. Topiramate also is approved for the prevention of migraine headaches in adults. more...



Topamax For Weight Loss

Topamax for Weight loss. Topiramate (Topamax) is used "off-label" as a weight loss pill. Weight loss > /=5% of baseline weight was achieved by 18% of subjects in the placebo arm vs 54, 61, and 67% of patients receiving topiramate 96, 192, and 256 mg/day, respectively. Weight loss > /=10% was achieved by 6 vs 29, 40, and 44%, respectively. How long will it take for topiramate for weight loss results? In clinical trials on weight loss and obesity topiramate was used at doses 96-250 mg per day. Mechanism of action: how Topiramate causes weight loss. The combination of phentermine and topiramate produces significant weight loss (up to 10%) in obese people over the course of one year, according to researchers at Duke University Medical Center 15 . Efficacy and safety of topiramate in obese subjects. The rationale and use of topiramate for treating neuropathic pain. The effect of topiramate on body weight and ghrelin, leptin, and neuropeptide-Y levels of prepubertal children with epilepsy. Weight loss and metabolic effects of topiramate in overweight and obese type 2 diabetic patients: randomized double-blind placebo-controlled trial. Topiramate, nutrition and weight change: a prospective study. The effect of topiramate on weight loss in patients with type 2 diabetes. more...



Topamax Drug and Medication User Reviews on RxList

Comment from: chrisca562, 25-34 Female on Treatment for 1-2 years (Patient) Published: January 16. Comment from: katydid, 45-54 on Treatment for 1-6 months (Patient) Published: June 26. Comment from: jlyons506, 45-54 on Treatment for 6 months - 1 year (Patient) Published: November 29. Comment from: HAWKEYE, 45-54 Female on Treatment for 6 months - 1 year (Patient) Published: June 07. Comment from: Joy4u2, 55-64 on Treatment for 1-2 years (Patient) Published: September 26. I was put on Topamax for depression and for weight problems last year at this time I weighed 220 I'm now at 165 I eat well and more healthy not wanting junk food any more. Comment from: 25-34 on Treatment for 1-2 years (Patient) Published: October 21. Comment from: mercury013, 25-34 on Treatment for 1-2 years (Patient) Published: March 04. I took Topamax for over a year, but not for the usual use. I eased off of it about a year sober and am soooo thankful this was around for me to take. Comment from: Alpaige, 25-34 on Treatment for 5-10 years (Patient) Published: September 21. My daughter and I both take Topamax for mood stabilization. I think this may not be the med for her at all. Comment from: papergirl, 35-44 on Treatment for 1-2 years (Patient) Published: January 06. If you can bear with the side effects for the first two months, it is so worth it. more...



Topiramate, Topamax for Migraine Side Effects and Dosage

The recommended final adult dose is 200-400 mg administered as two divided doses daily. The dose is then increased at 1 or 2 week intervals by 1 to 3 mg/kg/day administered in two divided doses. The target dose is 5 to 9 mg/kg per day in two divided doses. Migraine is treated 25 mg nightly for the first week then increased by 25 mg weekly up to a maximum dose of 100 mg administered in two divided doses. more...



Topamax Dosage, Titration, and Tapering

Week 1: 25 mg at bedtime. Week 2: 25 mg, twice a day. Week 3: 25 mg day dose, 50 mg bedtime dose. Week 4: 50 mg, twice a day. Weeks 5 - 7: maintain 50 mg, twice a day. Week 8: 50 mg day dose, 75 mg bedtime dose. Week 9: 75 mg, twice a day. Week 10: 75 mg day dose, 100 mg bedtime dose. Week 11: 100 mg twice a day. Maintain 100 mg twice a day. more...



How to Take Topamax for Weight Loss

How to Take Topamax for Weight Loss. A common side effect of taking Topamax is weight loss, induced by the drug's tendency to suppress the appetite. If you are still interested in trying Topamax, and all other methods of losing weight have not worked for you, then here's what to do. Be ready to state your argument about how other, more traditional, methods of losing weight have not worked for you in the past, and that you are aware of the side effects of Topamax but are willing to try it anyway. While some doctors will deny your request, arguing that the Food and Drug Administration (FDA) has not approved Topamax as a weight loss medication, others will be open to it, knowing that the FDA's lack of approval only means it can't be advertised as a weight loss product by its manufacturer. See if your doctor is open to the idea. Tell your doctor about any prescription or non-prescription medications, including birth control pills, that you are currently taking, because Topamax could interfere with their effectiveness. Follow your physician's directions exactly if he or she does prescribe Topamax for your weight loss intentions. You will only open yourself up to the possibility of more severe side effects, which in turn will most likely cause your doctor to cancel your treatment. Drink plenty of fluids while taking Topamax, because the drug raises your susceptibility of developing kidney stones. While some will disappear on their own after the first eight weeks or so, it is still important to report them to your doctor so he or she can evaluate whether you should stay on Topamax. more...



Topiramate in Bipolar and Schizoaffective Disorders

Her YMRS score was 1, and her BPRS score was 18. Her YMRS score was 0, and her BPRS score was 18. Her weight before topiramate was 284 lb (128 kg), which decreased to 242 lb (109 kg) at 1-month, 240 lb (108 kg) at 2-month, and to 228 lb (103 kg) at 3-month follow-up. Her weight was 176 lb (79 kg) before topiramate was added, and she had a DSM-IV diagnosis of bipolar disorder. Her YMRS score was 4, and her HAM-D score was 8. Her YMRS score was 8, and her HAM-D score was 7. Her YMRS score was 0, and her HAM-D score was 6. Her weight prior to topiramate treatment was 176 lb (79 kg), which decreased to 165 lb (74 kg) at 1-month, to 162 lb (73 kg) at 2-month, and to 156 lb (70 kg) at 3-month follow-up. Her weight was 180 lb (81 kg) before topiramate was added, and her DSM-IV diagnosis was schizoaffective disorder. She reported feeling depressed and was concerned about her weight. Her weight before topiramate treatment was 196 lb (88 kg). Her YMRS score was 3, her BPRS score was 19, and her HAM-D score was 6. Her YMRS score was 1, and her HAM-D score was 2. more...



Phentermine/Topiramate Extended - Release Capsules

2 – 4 A meta-analysis showed that orlistat led to a weight loss of 2.2 to 3.31 kg, but diarrhea and flatulence were among the most common adverse effects. The half-life is 20 hours for phentermine and 65 hours for topiramate. Doses were started at 3.75/23 mg and titrated to the target dose over a period of 4 weeks. Primary outcomes were percentage of change in body weight and the proportion of patients achieving at least a 5% reduction in weight. Women made up 70% of the patients, and 86% of patients were Caucasian. The average percentages of body weight loss were 7.8% with phentermine/topiramate CR 7.5/46 mg and 9.8% with 15/92 mg. The percentages of patients with a weight loss of 5% or more were 21% for placebo, 62% for the 7.5/46-mg dose and 70% for the 15/92-mg dose. Phentermine/topiramate CR 7.5/46 mg and 15/92 mg brought about more weight loss compared with placebo in patients with two or more weight-related comorbidities. At week 108, rates of weight loss were 1.8% for placebo, 9.3% for 7.5/46 mg, and 10.7% for 15/92 mg. More patients required antihypertensive and antihyperlipidemic medications in the placebo group than in the treatment groups, although no statistical analyses were completed for this observation. The most common adverse drug events (ADEs) (in 10% of patients or more) that occurred significantly more often with any dose of phentermine/topiramate CR than with placebo were constipation, paresthesia, and dry mouth. Dysgeusia, insomnia, and dizziness occurred in more than 10% of patients who received the 15/92-mg dose. 10 , 11 Other relatively common ADEs (affecting more than 5% of patients) in the low-dose treatment groups (7.5/46 mg) were dysgeusia and dizziness. Substantial reductions in serum bicarbonate levels were observed in the CONQUER trial, affecting one placebo patient, one patient receiving 7.5/46 mg, and seven patients receiving 15/92 mg. 9 Changes in mood and increased anxiety have occurred with the combination, and the risk is higher in patients with a history of depression. more...



Dosing and Side Effects of Topamax for Migraine Prevention

Dosing and Side Effects of Topamax for Migraine Prevention. Topamax (topiramate) is an anti-seizure medication approved by the FDA for the prevention of migraines. Topamax is available in 25mg, 50mg, 100mg, and 200mg tablets. Likewise, if a person is stopping Topamax, tapering the dose down is also recommended. What are the Potential Side Effects of Topamax? Treatment of this eye syndrome is to stop Topamax as quickly as possible, with the judgement and monitoring of the doctor who prescribed it. Also, like other anti-seizure medications , Topamax may increase a person's risk for suicidal thoughts and behavior. Side Effects of Topamax that are Dose-Dependent. These symptoms usually begin during the titration phase — when the medication is being slowly increased and are dose-dependent, meaning their likelihood is higher with higher doses of Topamax. If you are prescribed Topamax, it's important to not stop taking it or change the dosage without first consulting your doctor. For many people, Topamax is an effective preventive medication — but please take it correctly, safely, and under the care of your doctor. more...



Topamax : Weight Loss Plus - Psych Central Professional

Before wading into the muddy waters of whether Topamax is effective for bipolar disorder, let’s look at one thing that everybody can agree on: Topamax causes weight loss. In terms of efficacy, TCR‘s reading of the literature is that Topamax is probably not effective as monotherapy for acute mania, but that it works pretty well as adjunctive therapy for treatment resistant bipolar disorder. While TCR often slams drugs that have no better quality of evidence than this, we have to admit that there is an impressive number of published trials, and that the results are pretty consistently positive for Topamax (1). The typical result is that Topamax add-on results in improvement in 50-60% of patients. Susan Mc Elroy and her colleagues at the University of Cinncinatti devised a study to see whether adding Topamax to the existing regimens of bipolar patients would make any difference (2). These patients were then regularly assessed with standard rating scales, and the mean duration of treatment was about 7 months; the average final dose of Topamax was 245 mg QD. The results were fairly dramatic, in that adjunctive Topamax worked great for the 63% of patients who entered the study with hypomanic, manic, or mixed symptoms, but it didn’t do much of anything for most of the patients with bipolar depression. The bottom-line from the Mc Elroy study: use Topamax as add-on for your bipolar patients when they have some manic component to their presentation; it’s unlikely to be helpful when they are depressed. A nice chart review published by Marcotte and colleagues reviewed the results of adding Topamax to the regimens of 58 treatment refractory patients, most of whom had either bipolar disorder or schizoaffective disorder, and 44 of whom were rapid cyclers (3). more...



Topiramate and Weight Loss

Topiramate and Weight Loss. Unfortunately, weight loss, along with other gastrointestinal problems, is a side effect of the medication. Weight Loss. Not surprisingly, some individuals experience weight loss while taking topiramate. Prescribed for Weight Loss. Qsymia is sometimes prescribed, along with diet and exercise, to treat obesity and promote weight loss. more...



Possible Side Effects - TOPAMAX

TOPAMAX® may cause eye problems. TOPAMAX® may cause decreased sweating and increased body temperature (fever). TOPAMAX® can increase the level of acid in your blood (metabolic acidosis). If left untreated, metabolic acidosis can cause brittle or soft bones (osteoporosis, osteomalacia, osteopenia), kidney stones, can slow the rate of growth in children, and may possibly harm your baby if you are pregnant. Your healthcare provider should do a blood test to measure the level of acid in your blood before and during your treatment with TOPAMAX®. If you are pregnant, you should talk to your healthcare provider about whether you have metabolic acidosis. TOPAMAX® can harm your unborn baby. If you take TOPAMAX® during pregnancy, your baby has a higher risk for birth defects called cleft lip and cleft palate. Tell your healthcare provider right away if you become pregnant while taking TOPAMAX®. You and your healthcare provider should decide if you will continue to take TOPAMAX® while you are pregnant. Talk to your healthcare provider if TOPAMAX® has caused metabolic acidosis during your pregnancy. If you become pregnant while taking TOPAMAX®, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry. TOPAMAX® can slow your thinking and motor skills and may affect vision. These are not all the possible side effects of TOPAMAX®. more...



Topamax Dosage - Epilepsy Home Page

The recommended Topamax dosage for the prevention of migraines is 50 mg twice a day. The recommended dose of Topamax for migraine prevention is 50 mg twice daily. Second week - 25 mg twice daily. Fourth week - 50 mg twice daily. The recommended Topamax dosage for epilepsy as monotherapy (used alone) for adults and children age 10 and up is 200 mg twice daily. First week - 25 mg twice daily. Second week - 50 mg twice daily. Third week - 75 mg twice daily. Fourth week - 100 mg twice daily. Fifth week - 150 mg twice daily. Sixth week - 200 mg twice daily. more...



Topamax Dosage for Weight Loss

Topamax Dosage for Weight Loss. The Truth About Topamax Dosage for Weight Loss. Health care providers have started prescribing certain Topamax dosage for weight loss but only for certain situations. But because Topamax is not recommended or even recognized as drug or medication for weight loss by the US Food and Drug Administration (US FDA), this becomes an “off label” prescription or use of drug. Prescription of a minimum amount of Topamax dosage for weight loss falls under an “off label” prescription. Topamax has been prescribed for treatment of weight loss and obesity and to assist in the decrease of the occurrence of binge eating. However, prescription of Topamax for weight loss has also resulted in several undesirable side effects. This is the reason why Topamax will not be approved by the US Food and Drug Administration as a recommended prescription drug for weight loss because there is no balance. Because of this, despite the result, any amount of Topamax dosage and weight loss is not a good combination. more...



Topamax Dosage for Weight Loss

Topamax Dosage for Weight Loss. What is the proper Topamax dosage for weight loss? When considering Topamax dosage for weight loss, one must take into account the risks of the medication vs. While the above may sound like a dream come true for people desperate to lose weight, Topamax is a powerful drug, and weight loss may come at a price. What Is the Right Topamax Dosage for Weight Loss. The Topamax dosage for weight loss can be as low as 25 mg per day or as high as 800 mg per day-usually split into two doses. When considering Topamax for weight loss, you may want to factor the following into your decision: The use of Topamax for weight loss is an off-label use. It is very likely that relatively small doses of Topamax can cause weight loss in many patients. It is important to note, however, that the FDA has not approved Topamax for the treatment of weight loss. more...



Getting Rich and Skinny off Migraine Medication : Topamax Part I

One of the first things my Neurologist said to me about Topamax was: But still I remained positive that I was only going to suffer supermodel anorexia and none of the other possible reactions. “And this drug can interfere with the contraceptive pill, so you don’t want to get pregnant!” My Neurologist also assured me that most of the side effects would wear off and the scary ones, like going blind (I’m exaggerating for dramatic effect), would be apparent very quickly. I ran to Mum and, between lapping up water like a dog from the two jugs of water I was holding, said: He explained it actually takes some time for Kidney stones to develop, and as I’d only been on the drugs for 2 weeks it was unlikely. By now you might also have guessed the second bizarre side effect I was suffering. In the end it turned out Dad was right, I was not dying of Kidney stones. But the thirst was to such an extent that I could do nothing else all day but lie in bed and drink. Was I really going to be the first person to die from water explosion? Incidentally, I looked again at the side effects of Topamax and sure enough “Increased thirst and drinking abnormally large amounts of fluid” was listed. I do realize that of all the listed side effects, I was pretty lucky. more...



Topamax 25 mg Tablets - Summary of Product Characteristics

Addition or withdrawal of phenytoin and carbamazepine to adjunctive therapy with Topamax may require adjustment of the dose of Topamax. In patients with or without a history of seizures or epilepsy, antiepileptic drugs (AEDs) including topiramate should be gradually withdrawn to minimize the potential for seizures or increased seizure frequency. The recommended initial target dose for topiramate monotherapy in adults is 100 mg/day to 200 mg/day in 2 divided doses. Subsequently, at weekly or bi-weekly intervals, the dose should be increased by 25-50 mg/day and taken in two divided doses. The recommended total daily dose of Topamax (topiramate) as adjunctive therapy is approximately 5 to 9 mg/kg/day in two divided doses. The recommended total daily dose of topiramate for prophylaxis of migraine headache is 100 mg/day administered in two divided doses. In patients with impaired renal function (CLCR ≤ 70 m L/min) topiramate should be administered with caution as the plasma and renal clearance of topiramate are decreased. In patients with moderate to severe hepatic impairment topiramate should be administered with caution as the clearance of topiramate is decreased. The mechanism of this risk is not known and the available data do not exclude the possibility of an increased risk for topiramate. In hepatically-impaired patients, topiramate should be administered with caution as the clearance of topiramate may be decreased. If metabolic acidosis develops and persists, consideration should be given to reducing the dose or discontinuing topiramate (using dose tapering). Topiramate should be used with caution in patients with conditions or treatments that represent a risk factor for the appearance of metabolic acidosis. more...



Topamax

I had been up to 100mg in a split dose but I woke with double vision and determined that I would reduce the dose. It was around the time I was taking Topiramate, but I’m not sure that was the cause. After being on it for 2 years and experiencing the typical side effects i.e. That was the good now for the bad….when I woke up after that energy spurt I had the most horrible migraine I had ever experienced and I’ve had them for probably 20 years or so. I have wanted to tell this story for almost 2 years and I’m happy to finally have the opportunity to do just that! Find the dosage that works for you. I was also prescribed Topamax starting with 50mg twice a day and my neurologist increased the dosage to 200mg twice a day. After that, I backed off the dose to 150 mg, and I was fine, for a while. If you have had stones in the past, this is your WARNING. Trying to deal with the side effects and still dealing with migraines, so I’m not sure if it’s going to work for me, but I’m seeing *some* improvement. The bottom line with topiramate is that going up slowly in dosage and taking your time is really vitally important. I have had a reduction of the pins and needles/burning sensations on the 75 mg dose. This isn’t the choice everyone will want to make, but I am glad I was given that choice and we could plan accordingly. more...



Topiramate : MedlinePlus Drug Information

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. You should be sure that you receive topiramate and not the similar medication each time you fill your prescription. Be sure that the prescription your doctor gives you is clear and easy to read. Do not take any medication unless you are certain it is the medication that your doctor prescribed. Read the information carefully and ask your doctor or pharmacist if you have any questions. Tell your doctor and pharmacist if you are allergic to topiramate, any other medications, or any of the ingredients in topiramate tablets, sprinkle capsules, and extended-release capsules. Your doctor will probably tell you not to take metformin if you have metabolic acidosis and you are taking this of medication. If you are pregnant or plan to become pregnant, your doctor may prescribe a different medication instead of topiramate because topiramate may harm the fetus. Talk to your doctor about what type of birth control you should use, because taking topiramate may decrease the effectiveness of some types of birth control. If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking topiramate. If you are taking topiramate to control seizures, you should know that you may continue to have seizures during your treatment. Your doctor will probably tell you not to drink alcohol while taking topiramate. You and your doctor will decide whether the risks of taking an anticonvulsant medication are greater than the risks of not taking the medication. Talk to your doctor about increasing the amount of food you eat if you lose weight while you are taking topiramate. Talk to your doctor about the risks of taking topiramate. more...



FDA Approves Phentermine - Topiramate Combo for Weight Loss

The agency's statement also notes that the drug can increase heart rate, which warrants regular monitoring, and should be used with caution in people with recent unstable heart disease or stroke. In February, an FDA advisory panel voted overwhelmingly in favor of the drug's approval for obesity, despite some concerns about possible adverse effects, as reported by heartwire . That allowed the FDA to consider the REMS for Qsymia that Vivus had submitted on April 4 [2]. Many on the advisory panel had stated that their vote favoring Qsymia-it was ultimately 20 to 2-assumed that the company would in fact submit and implement a REMS, parts of which Vivus described at the hearing. Both the FDA and its advisory committee had decided against approval of Qsymia during its first round of consideration in October, 2010, pending a more comprehensive safety assessment. more...



Topiramate Adverse effects

Topamax, Topamax Sprinkles: 25 mg PO q12hr initially; may increase by 50 mg/day at weekly intervals to 200 mg PO q12hr. Trokendi XR, Qudexy XR: 50 mg PO q Day initially; may increase by 50 mg/day at weekly intervals for first 4 weeks, then 100 mg/day for weeks 5 to 6; target dose is 200-400 mg/day for partial onset seizures and 400 mg/day for generalized seizures. Topamax, Topamax Sprinkles: 25-50 mg/day PO initially; increase by 25-50 mg/day at weekly intervals to 100-200 mg q12hr for partial onset seizures and 200 mg q12hr. Trokendi XR, Qudexy XR: 25-50 mg PO q Day initially; increase by 25-50 mg/day at weekly intervals to achieve effective dose; not to exceed 200-400 mg/day. Topamax, Topamax Sprinkles: 25-50 mg/day PO initially; increase by 25-50 mg/day at weekly intervals to 100-200 mg q12hr. Week 2: 25 mg PO BID. Week 4: 50 mg PO BID. Increase by 25 mg/day every week to no more than 200 mg/day. Initial: 25 mg PO q Day week 1. more...



Topamax Dosage Guide

Adults 17 Years of Age and Over - Partial Onset Seizures, Primary Generalized Tonic-Clonic Seizures, or Lennox-Gastaut Syndrome. The recommended total daily dose of TOPAMAX® as adjunctive therapy in adults with partial onset seizures is 200 to 400 mg/day in two divided doses, and 400 mg/day in two divided doses as adjunctive treatment in adults with primary generalized tonic-clonic seizures. In the study of primary generalized tonic-clonic seizures, the initial titration rate was slower than in previous studies; the assigned dose was reached at the end of 8 weeks [see Clinical Studies (14.1) ]. The recommended total daily dose of TOPAMAX® as adjunctive therapy for pediatric patients with partial onset seizures, primary generalized tonic-clonic seizures, or seizures associated with Lennox-Gastaut syndrome is approximately 5 to 9 mg/kg/day in two divided doses. Dose titration should be guided by clinical outcome. In the study of primary generalized tonic-clonic seizures, the initial titration rate was slower than in previous studies; the assigned dose of 6 mg/kg/day was reached at the end of 8 weeks [see Clinical Studies (14.1) ]. ​The recommended total daily dose of TOPAMAX® as treatment for adults and adolescents 12 years of age and older for prophylaxis of migraine headache is 100 mg/day administered in two divided doses (Table 3). The recommended titration rate for topiramate for migraine prophylaxis to 100 mg/day is: Table 3: Migraine Prophylaxis Titration Schedule for Adults and Adolescents Patients 12 Years and Older. Dose and titration rate should be guided by clinical outcome. more...



Topamax for Weight Loss

Topamax for Weight Loss? My physician has given me a prescription for Topamax for weight loss support. My physician told me I'm not at risk for breast or lung cancer or lots of other diseases judging by my lifestyle and family history, but I am at risk for stroke or heart attack if I don't lose around 35-40 lbs. I'm well aware that programs like Weight Watchers are successful and that patients don't keep weight off unless they change their eating habits, but I'm going to jump start my weight loss with the Topamax. I'm hoping not to be lectured, but rather to hear about anyone's experience with Topamax for weight loss. I have only been on Topamax for 1 week, and maybe it's psychological, but my appetite seems to be increasing. I've been on a diet for 5 weeks, and I've only lost 13 lbs. And asked him to take me off of my Abilify for Bipolar and change me to something that didn't cause weight gain . I don't know if that will change my cravings for sweets, but I certainly hope so. more...



Topamax weight loss dosage. Express Delivery, Best Prices

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